Paclitaxel, doxorubicin, and vincristine, known as MRP7 or MRP1 substrate drugs, were used as positive controls for different cell lines, and cisplatin as non-substrate for both MRP7 and MRP1 was used as the negative control
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B1b cells are able to undergo somatic hypermutation and therefore have a more expanded IgM repertoire that is primarily secreted following stimulation through a TLR or BCR 3,126
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Akbarali HI, Muchhala KH, Jessup DK, Cheatham S (2022) Chemotherapy induced gastrointestinal toxicities